Senior Machine Learning Engineer
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Looking for a machine learning engineer job in San Francisco? Choose from 96 open roles at 39 employers. Explore real salary data and skills breakdown across remote, hybrid and on-site roles.
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The roles on this page cover a wide spectrum of ML work. At one end, postings like the Machine Learning Engineer at Latent AI focus on owning end-to-end production systems — training and fine-tuning large language models, building evaluation frameworks, and managing accuracy-latency-cost tradeoffs for clinical workflows. Responsibility for safety and fairness appears repeatedly: the Pinterest Responsible AI posting centres on identifying and mitigating bias across generative AI and recommender systems, while the Anthropic Safeguards ML Infra role sits closer to infrastructure, owning deployment pipelines for safety classifiers and on-call production operations. Recommendation systems and monetisation engineering feature prominently across multiple titles from Pinterest and Airbnb. The Airbnb Trust role combines fraud detection with LLM and agent work. Further along the spectrum, the Pinterest senior manager posting involves leading teams, translating research into production, and mentoring. The Swayable role is narrower, focusing on scientific computing and analytics rather than deep learning infrastructure.
Python and LLMs are the most widely mentioned skills across these postings, followed closely by PyTorch. PhD and Master's degree appear in roughly half the postings each, though these are mentions in job descriptions rather than stated requirements, and the small sample means the proportions should not be treated as definitive market signals. Publications, reinforcement learning, and agent-based work appear in a meaningful minority. TensorFlow is mentioned noticeably less often than PyTorch.
The employers' own advertised ranges, for individual roles at different levels — not an average and not a market rate.
Most postings in this set are listed as onsite, with a smaller portion hybrid. A minority allow remote work. Work-mode is stated for all postings on this page, so there are no unknowns in the counts. The Pinterest senior manager role is an example of an exception within what is otherwise a predominantly office-based set: its summary notes that the position can be located anywhere in the US with in-office visits one to two times per quarter. Candidates should confirm current arrangements directly with each employer, as stated modes can change.
Jobs checked 2 hours ago. · Guide reviewed 14 September 2026.
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