Research Scientist Jobs in San Francisco, USA

Looking for a research scientist job in San Francisco? Choose from 68 open roles at 23 employers. Explore real salary data and skills breakdown across remote, hybrid and on-site roles.

68 Open roles
23 Companies hiring
371K Average salary

What do Research scientists in San Francisco work on?

The roles on this page divide broadly into two clusters. Most are centred on large language models and AI systems: designing evaluations, running pre-training and post-training experiments, improving model behaviour, and building agentic systems. A smaller but distinct group sits in the life sciences, including wet-lab chemistry, computational biology, and AI tooling for scientific research.

For the AI-focused roles, day-to-day work commonly involves running experiments on model capabilities, designing benchmarks, working with reinforcement learning, and contributing to safety or interpretability research. Two of the sample summaries from Databricks — Principal AI Research Scientist, Research Director – AI Scaling and Principal Research Scientist – Scaling — describe leading teams and setting roadmaps for LLM training efficiency.

The life sciences postings at Anthropic range from hands-on chemistry — the Research Scientist, Life Sciences (Chemistry) role involves bench synthesis and characterisation — to computational pipeline work in the Research Scientist, Life Sciences (Computational) posting, to building agentic tools for scientific tasks in the Research Scientist, Life Sciences role.

Skills and experience employers ask for

Skills counts reflect how often a term appears in posting descriptions across this sample of postings, not whether each skill is strictly required. Evaluation is the most frequently mentioned term, followed by LLMs and reinforcement learning. PhD and publications appear in roughly half the postings, signalling that academic research backgrounds are commonly referenced, though the framing varies by role and employer. Python and PyTorch appear at similar rates.

Evaluation 72%
LLMs 51%
PhD 50%
Reinforcement learning 47%
Publications 46%
Agents 34%
Python 32%
PyTorch 32%
Master's degree 24%
Fine-tuning 21%
Distributed training 18%
A/B testing 18%
Statistics 15%
APIs 12%

Research Scientist roles that state a salary

The employers' own advertised ranges, for individual roles at different levels — not an average and not a market rate.

San Francisco office, hybrid or remote?

The majority of postings on this page are listed as onsite, meaning a physical San Francisco presence is expected. A notable share are hybrid, though the specific in-office cadence is not stated in most cases. Only a very small number are listed as fully remote. No postings have an unknown work mode. Candidates should treat each posting individually, as hybrid terms differ by employer and are not standardised across this set.

Make your application specific to the work

  1. Identify your research focus These roles span AI systems, safety, life sciences, and scaling, so review the sample titles and summaries to find postings that match your specific background before applying broadly.
  2. Check credential signals carefully PhD and publications are mentioned in a large share of these postings; where they appear, review whether the language is prescriptive or preferred, as this varies by role.
  3. Prepare relevant work samples Several summaries reference a track record of research projects or published work, so gather preprints, papers, or documented project outcomes relevant to the specific sub-field you are targeting.
  4. Note work mode before applying Most postings expect onsite presence in San Francisco; confirm the stated work mode for each specific role, as remote or hybrid availability is not universal across this set.

Questions about Research Scientist jobs in San Francisco

A PhD is mentioned in a large proportion of the postings on this page, but it is not universal. Some postings reference a master's degree, and a minority do not state a degree requirement. Whether a PhD is mandatory or preferred varies by role, so reading each posting individually is necessary.

Pay ranges are only stated in a minority of postings on this page. All the advertised ranges visible here come from OpenAI, specifically for Research Engineer or Research Scientist positions in their Personal AGI and Health teams. Those ranges run from $380,000 to $500,000. No other employer on this page has published a pay range in these postings.

Remote availability is very limited on this page. The clear majority of postings are onsite, with a smaller portion listed as hybrid. Only two postings are listed as fully remote. Candidates expecting flexible arrangements should check each posting directly.

The seniority level is not stated in a large portion of the postings. Among those where it is indicated, senior and lead positions make up the bulk, with director and manager levels each appearing once. There is one intern posting and one junior-level posting in this set.

Yes. Anthropic has several postings specifically in life sciences, covering computational biology, hands-on chemistry including synthesis and characterisation, and AI tooling for scientific tasks such as bioinformatics and literature synthesis. Lila Sciences also has postings in this set, though detailed summaries for those roles are not included in the sample.

Jobs checked 2 hours ago. · Guide reviewed 9 September 2026.